Now that we understand some of the variables involved with evaluating exposure to toxic chemicals, it’s time to move forward with the Toxin Research Project. The first step is to decide which toxin you want to research. You are welcome to select anything of interest to you, as long as you can identify a specific molecule in the PubChem (NCBI) database AND you can find an appropriate LD50 for the molecule.
For inspiration, the websites below can help get you started:
- Alcohol (ethyl alcohol – beer, wine)
- Alcohol (mixed with other drugs)
- Arsenic (contaminated water)
- Benzene (gasoline, cigarettes, industrial processes
- Benzodiazepenes (Xanax)
- Caffeine (beverages, chocolate)
- Copper (industrial processes)
- CBD (marijuana)
- Formaldehyde (smoking, manufacturing)
- Glyphosate (weed killer)
- Iron (vitamins)
- Lead (Flint water crisis)
- LSD (ergot fungus)
- Methamphetamines (meth, MDMA/Ecstasy)
- Monosodium glutamate (food additive)
- Nicotine (vaping and cigarettes)
- Opioids (heroin, Vicodin)
- Oxycodone (OxyContin)
- Psilocybin (magic mushrooms)
- Silver (argyria)
- THC (marijuana)
- Toluene (gasoline)
For this part of your work, you need to create a Google Slides document. All of your Toxin Research Project work will go into the Google Slides. Instructions for completing this part of the work:
- Create a Google Slides document
- Title the document “Toxin Research Project – Your Name”
- Example: Toxin Research Project – Pierre Swart
- Slide 1 must include:
- Name of the molecule
- A link to the PubChem database entry.
- An image of the molecular structure.
- How someone might be exposed to the molecule (i.e. a specific food, drink, plant, animal, type of work, a location in the environment where it naturally occurs, etc).
- The LD50 for the molecule (including species and route of administration) most relevant to the route and type of exposure you selected.
The molecule name, image, and LD50 for the molecule should all be found in the PubChem database. If you select a toxin from the list above, the linked article will provide you with information about exposure to the molecule. If you pick a toxin not on the list, you will need to do that research on your own.
Need help? You have options:
- Click here and watch a video of Mr. Swart guiding you through the process of conducting the research to complete Slide 1. You will also be provided with an example of Slide 1.
- Attend office hours on Tuesday and/or Thursday
- Email Mr. Swart with specific and detailed questions.
Finally, I would like to be able to post these online to share with each other. Please be creative in your layouts and make sure your name is not actually on the slide anywhere. Your name should only be in the title of the document. Have fun!
When finished with Slide 1, return to Weeks 34-35 – How Much Is Too Much? and continue working.