We began with the Lesson 47 PowerPoint ChemCatalyst to help get students thinking about mirror images. We then watched a short video about chirality (below):
Students then received the Lesson 47 Worksheet, working in pairs to model the compounds using the class set of molecular modeling kits. The worksheet concluded with students hypothesizing whether L-carvone will smell like D-carvone, and then testing their hypothesis. For homework, students were assigned textbook questions 5-8.
Update: January 18
Given the challenging nature of the subject matter in Lesson 47, we used most of the class period to review the homework, build molecules, and discuss the relationship between isomers and chirality. Notes from the overhead are shown below:
Want more? Check out the blog post Perhaps looking-glass milk isn’t good to drink for an overview of Lewis Carroll, looking-glass milk, and L- and D-carvone. Want more? Joanna Shawn Brigid O’Leary from Rice University published an even more extensive investigation of how Lewis Carroll (author of Alice in Wonderland and Through the Looking Glass) weaved biochemistry into his fiction. Her paper (available as a PDF), WHERE ‘THINGS GO THE OTHER WAY’: THE STEREOCHEMISTRY OF LEWIS CARROLL’S LOOKING-GLASS WORLD is well worth the read. Perhaps it will even inspire students to read the book before the movie is released in theaters on May 27!