Central Dogma: Case Study of Cystic Fibrosis

Because of the short week, today was a full schedule Friday.  We took advantage of the longer class period by learning about the stop codon, focusing on cystic fibrosis as a model disease caused by a genetic mutation which introduces a premature stop codon in about 10% of people with CF.  After watching an inspiring music video about a 15-year-old young man with CF, students learned more about the disease and genetic mutations in general.  We finished with a game where students practiced converting amino acid sequences to RNA and then replacing individual bases to create stop codons.  The lesson plan, along with example sequences from the game can be found here.

Leave a Reply

Please log in using one of these methods to post your comment:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s